After our miscarriage this summer, my RE suggested that I do the battery of blood tests for recurrent pregnancy loss to dig deeper into what might be going on. My first pregnancy in 2008 ended at 21 weeks gestation and this one at 7.5 weeks. We gave birth to our rainbow baby in July 2010. All pregnancies have been the result of fertility treatments, as we have struggled with infertility over the course of 5 years.
After our stillbirth in 2008, we wanted to make sure we were tested for everything under the sun that could have possibly caused a later trimester loss. Everything came back normal at the time and the loss of our son was considered a fluke. The biopsy of the baby that we lost this summer did not yield results.
Evidently the bloodwork for RPL is a broader battery of tests than I had done a few years back following our stillbirth. I now finally have learned that I have a single MTHFR gene mutation as well as low Protein S. I have been prescribed Folgard for MTHFR. My Protein S level has been tested twice over the past few months, and although it is below the normal range- the hematologist who reviewed my paperwork has deemed that I do not have the disorder and therefore would not be prescribed lovenox in a future pregnancy.
Even though the doctors could not give a definite reason for our stillbirth, blood clotting was a strong possibility and in my gut have felt it was the reason. So I guess this news of potential immune issues doesn't shock me- I just wish I knew more about it and wish I knew sooner. With our rainbow baby, I took baby aspirin throughout the pregnancy. However, it was treated more as "it can't hurt" than an actual preventative measure by my doctors. I was told not to bother taking it during this last pregnancy, which was short-lived.
I've just moved to a new state and need to start over with doctors (ugh!). In addition to meeting with a new RE soon I also would like to talk to a hematologist in person about the low Protein S and treatment thereof.
This is new information for me. If anyone out there can offer suggestions, share experiences related to MTHFR and/or low Protein S/Protein S Deficiency as it relates to infertility and baby loss, I would appreciate hearing from you.